Andreas Radbruch-01

Andreas Radbruch

DRFZ
Germany

Education: 1980: PhD at the University of Cologne, Germany. Experience: since 1996: Scientific Director of the Leibniz-Institut “Deutsches Rheuma-Forschungszentrum” (DRFZ)
1998: Professor for Rheumatology at the Charité – Universitätsmedizin Berlin. Awards and honours
(last 5 years): 2019: President of the European Federation of Immunology (EFIS), 2017 Blondel medal of the city of Aachen/Germany
2017: Council member of the Berlin-Brandenburg Academy of Sciences and Humanities (BBAW)/Germany, 2015: Spokesman of Section C of the Leibniz Association
2014-2016: President of the International Society for Advancement of Cytometry (ISAC)
2014: Avery Landsteiner Award. Research: refined research aiming at a molecular understanding of immune reactions and immunological memory. Focus on the regulation of antibody class switching in activated B lymphocytes and analysis of the shaping of antibody idiotypes by somatic mutation in B lymphocytes. Developed the MACS technology and the cytometric secretion assay. Contributed significantly to understanding of Th1 and Th2 cytokine memory, its imprinting and plasticity in effector and memory T lymphocytes. Identified critical molecular adaptations of Th effector memory cells to chronic inflammation. Described the organization of memory plasma cells and memory T helper (Th) lymphocytes in bone marrow. Identified memory plasma cells secreting pathogenic antibodies as novel target in chronic immune-mediated diseases.