Kiyoshi Takeda graduated from Osaka University School of Medicine in 1992 and conducted his PhD work at the Graduate School of Medicine, Osaka University under the supervision of Prof. Shizuo Akira. He was an assistant professor in Hyogo College of Medicine, and Research Institute for Microbial Diseases, Osaka University, where he worked on the mechanisms for Toll-like receptor-dependent pathogen recognition. In 2003, he became a professor at Medical Institute of Bioregulation, Kyushu University, and then moved to Graduate School of Medicine, Osaka University in 2007. Now, he is a director and professor of Immunology Frontier Research Center, Osaka University. His research activity is focused on understanding the pathogenesis of inflammatory bowel diseases, particularly the analysis on how intestinal homeostasis is maintained by mucosal innate immune cells and epithelial cells. He is also analyzing how microbiota resides in the intestine without evoking inflammatory responses and influences the host health.