Daniel Mucida
The Rockefeller University
USA
At the surface of the intestinal lining, immune responses are carefully balanced: Invasive pathogens must be eliminated or excluded, while nutrients and trillions of commensal microbes must be tolerated. Dr. Mucida studies how the immune system associated with intestinal mucosae maintains this careful balance by generating efficient protective responses without jeopardizing its tolerance to innocuous foreign substances.
EDUCATION
B.S. in biochemistry and immunology, 2000
Federal University of Minas Gerais
Ph.D., 2005
University of São Paulo and New York University
POSTDOC
La Jolla Institute for Allergy and Immunology, 2006–2010
POSITIONS
Assistant Professor, 2010–2016
Associate Professor, 2016–
The Rockefeller University
SELECTED PUBLICATIONS: (FIVE MOST RECENT, OR MOST REPRESENTATIVE)
– Gabanyi I, Muller P et al. (2016). Neuro-immune interactions drive tissue programming in intestinal macrophages. Cell 2016 Jan 28; 164(3):378-91.
– Sujino T et al. (2016). Tissue adaptation of regulatory and intraepithelial CD4+ T cells controls gut inflammation. Science Jun 24;352(6293):1581-6.
– Hoytema van K. DP et al. (2017). Intestinal epithelial and intraepithelial T cell crosstalk mediates a dynamic response to infection. Cell 171(4):783-94.
– Tavazoie MF et al. (2018). LXR/ApoE activation restricts innate immune suppression in cancer. LXR/ApoE Activation Restricts Innate Immune Suppression in Cancer. Cell 172(4):825-840.e18.
– Esterhazy D et al. (2019). Compartmentalized gut lymph node drainage dictates adaptive immune responses. Nature In press.